Principal Investigator:  Dr. Jane S. Paulsen

Study Description:  COHORT is a multi-site, long-term observational study. Our goal is to collect information in order to learn more about HD (such as potential treatments, planning of future experimental drug studies, and work toward postponing the onset or slowing the progression of HD). The study will be open to both adults and children who have clinically diagnosed HD, and to adults who are part of HD families.

Participation in COHORT is voluntary, and visits will be scheduled annually for as long as individuals are able and choose to participate. At the initial visit (year one) a blood sample will be drawn for genetic testing of CAG repeat and other possible biomarkers. Medical and neurological evaluations will be performed at each yearly visit; these include standardized assessments of movement, thinking, memory, ability to perform everyday tasks and behavior. Participants will be asked to provide information about medical history and their current medications.