Zita Sibenaller, PhD, Senior Research Scientist coordinates the efforts of Molecular Neurosurgery
Laboratory and Central Nervous System Tissue Bank in the Department of
Neurosurgery.
The laboratory and tissue bank function in closely related interdepartmental
projects in clinical and preclinical studies with the Glioma Research
Laboratory (Traynelis and Sahu) and the Neurogenetics laboratory (Foltz)
in addition to providing support for other investigators.
Specific aims of the research efforts include:
- Molecular genetic analysis of primary and secondary central nervous
system neoplasia.
- Development of integrated bioinformatics data for translational
studies related to central nervous system neoplasia including clinical,
pathological, radiographic and genetic data sets.
- Study of the central nervous system precursor (stem cells) and their
role in developmental neurobiology and neoplastic transformation.
- Maintenance of a central repository for human central nervous system
tumor tissue for development of translational research projects and
collaborative efforts.
The goal of these combined efforts is to provide a foundation for focused
individual resident and student projects and support for translational
studies aimed at understanding the process of neoplastic transformation
in the central nervous system. Both human and animal models are incorporated.
The Central Nervous System Tissue Bank was initiated with support from
the Carver Foundation and is maintained as a resource by the Department
of Neurosurgery
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