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Patient Information: Chronic Pelvic Pain

Prozac Therapy

Studies have shown that there is a link between depression and chronic pain of any type. Symptoms of depression include:
• Feelings of sadness or irritability.
• Loss of interest or pleasure in activities.
• Change in weight or appetite.
• Sleep problems.
• Feeling guilty, hopeless, helpless.
• Fatigue, decreased energy.
• Thoughts of suicide.

All of us go through ups and downs. It is not surprising that people with chronic pain have more downs than ups. Many experts think that part of the problem is a "chemical imbalance" in the brain. This can often be improved by giving antidepressant medicationsSSRI's are a newer type of antidepressent.

HOW DOES IT WORK? It is thought that Prozac works by its action in the brain. A substance called "endorphin" is increased with antidepressant use. Endorphins are made by our brains and actually decrease pain - your body's natural painkiller.

DOSE: Consult your provider before changing your dose. It can take from 1-4 weeks for the drug to start working. It is a good idea to wait at least one month before changing the dose.

SIDE EFFECTS: Most people taking SSRI's do not have side effects. The most common side effects are tremors, drowsiness, sweating and nervousness. Many side effects will stop after a week or so. As with all drugs, many other symptoms have been reported but are rare. Any concern about side effects should be discussed with your provider.

COST: Drug stores vary in the amount they charge so it is helpful to call and check on prices.

SAFETY: Much has been written in the press lately regarding the safety of SSRI's. Most of the concern has been whether or often increases the risk of suicide. It is helpful to note that depressed persons are at risk for suicide. Most mental health experts think that the suicides are the result of the illness and not SSRI use. Many studies have shown that SSRI's are safe. Therefore, we feel comfortable prescribing Prozac to our patients. It is important that thoughts of suicide be discussed with a professional especially if they become more frequent or more serious.

Peer Review Status: Internally
Peer Review Date: 2004