Thomas D. Brown, PhD

Richard and Janice Johnston Chair of Orthopaedic Biomechanics
Director, Orthopaedic Biomechanics Laboratory

Education

• Case Institute of Technology, Cleveland, OH , Metallurgy
• BS, Mechanical Engineering University of Maryland, College Park, MD, 1972
• MS , Mechanical & BioEngineering, Carnegie-Mellon University, Pittsburgh, PA, 1973
• PhD, Mechanical & BioEngineering, Carnegie-Mellon University, Pittsburgh, PA, 1976

Research and Professional Experience

• 1975-1976 Senior Engineer, Westinghouse Research and Development Center, Churchill, PA
• 1976-1981 Research Assistant Professor of Orthopaedics and Civil Engineering, University of Pittsburgh
• 1981-1983 Research Associate Professor of Orthopaedics and Civil Engineering, University of Pittsburgh
• 1983-1987 Associate Professor of Orthopaedic Surgery and Biomedical Engineering, University of Iowa
• 1987-1997 Professor of Orthopaedic Surgery and Biomedical Engineering, University of Iowa
• 1997-Present Richard and Janice Johnston Chair of Orthopaedic Biomechanics, University of Iowa

Member of ASME; ASTM (Chairman, F04 Task Group on External Fixation); Society for Biomaterials; ORS [Membership Committee 1984–1988, (Chairman 1986–1987), Board of Directors 1986–1987, 1997–2000, Program Committee 1987–1988, 1991–1992, 1996–1998, (Chairman 1998–1999), President 2001–2002]; Society for Experimental Mechanics; American Society of Biomechanics [Program Committee 1985–1988, (Chairman 1987), Executive Committee 1986–1987, 1992–1995, Membership Committee 1988–1992, (Chairman 1991–1992), President 1993–1994]; AAOS (Associate 1986–Present, Committee on Biomedical Engineering 1991–1997, Program Committee 1998–2001; Committee on Research 2002–2006); The Hip Society (Associate 1985–Present, Education Committee 1999–2002); Editorial Consultants Panel, Journal of Biomechanics 1984–Present; Associate Editor, Journal of Orthopaedic Research 1987–1923; Associate Editor, ASME Journal of Biomechanical Engineering 1988–1993; Consulting Editor for Research, Journal of Bone and Joint Surgery 1989–Present; Advisory Panel, International Journal of Orthopaedic Trauma 1995–Present; Editorial Board, Journal of Musculoskeletal Research 1996–present; Editorial Board, Journal of Orthopaedic Trauma, 2005-Present; NIH Orthopaedic and Musculoskeletal Study Section (Regular Member 1989–1993).

Honors:

General Motors Scholar; Elected to Tau Beta Pi, Pi Tau Sigma, and Sigma Xi Honorary Societies; ASTM Research Prize in Mechanical Metallurgy; NIH Training Grant Recipient; Borelli Award, ASB; Kappa Delta Award, AAOS/ORS; Frank Stinchfield Award (3 times), The Hip Society; Fellow, AIMBE; Clinical Biomechanics Award (2 times), ASB; William Harris Award, ORS; Microstrain Award (2 times), ASB; Mark Coventry Award, The Knee Society; OREF Clinical Research Award, AAOS.

Relevant Publications: (228 full-length papers, 1,262 abstracts/presentations)

Lundberg HJ, Stewart KJ, Callaghan JJ, Brown TD. Kinetically-critical sites of femoral head roughening for wear rate acceleration in total hip arthroplasty. Clin. Orthop. Rel. Res. Symposium: Materials and Tribology in Total Hip Replacement, Jan 2005;430:89–93.

Heiner AD, Callaghan JJ, Brown TD. A Laboratory simulation for morselized bone graft fusion: Apparent modulus under operatively-based femoral impaction kinetics. J. Biomech. 2005 Apr;38 (4):811–818.

Beardsley CL, Anderson DD, Marsh JL, Brown TD. Interfragmentary surface area as an index of comminution severity in cortical bone impact. J. Orthop. Res. 2005;23(3):686–690.

Pedersen DR, Callaghan JJ, Brown TD. Activity-dependence of the safe zone for impingement versus dislocation avoidance. Med. Eng. Phys. 2005 May;27(4):323–328.

Tochigi Y, Rudert MJ, Brown TD, McIff TE, Saltzman CL. The effect of implantation accuracy on range of movement of the Scandinavian Total Ankle Replacement. J. Bone Joint Surg. (Br.) 2005;87-B:736–740.

Nielsen JK, Saltzman CL, Brown TD. Determination of ankle external fixation stiffness by expedited interactive finite element analysis. J. Orthop. Res. 2005;23:1321–1328.

Tochigi Y, Rudert MJ, Amendola A, Brown TD, Saltzman CL. Tensile engagement of the peri-ankle ligaments in stance phase. Foot Ankle Int. 2005;26(12):1067–73.

Goetz JE, Chung YY, Zimmerman DL, Pedersen DR, Robinson DA, Conzemius MG, Brown TD. Steroid-induced versus cryoinsult-induced femoral head osteonecrosis: Statistical measurement of histologic abnormality focalization. J. of Musculoskeletal Res. 2005 Dec;9(4)161–172.

Evans R, Conzemius MG, Robinson DA, McClure SR, Dahlberg JA, Brown TD. Single case designs in veterinary research. Am. J. Vet. Res. 2006 Jan;67(1):189–95.

McKinley TO, Rudert MJ, Koos DC, Pedersen DR, Baer TE, Tochigi Y. Brown TD. Contact stress transients during functional loading of ankle step-off incongruities. J. Biomech. 2006;39:617–626.

McKinley TO, Rudert MJ, Koos DC, Pedersen DR, Baer TE, Tochigi Y, Brown TD. Stance-phase aggregate contact stress and contact stress gradient changes resulting from articular surface stepoffs in human cadaveric ankles. Osteoarthritis Cartilage. 2006 Feb;14(2):131–8.

Bouchard SM, Stewart KJ, Pedersen DR, Callaghan JJ, Brown TD. Design factors influencing performance of constrained acetabular liners: Finite element characterization. J. Biomech. 2006;39(5):885–893.

Lundberg HJ, Stewart KJ, Pedersen DR, Callaghan JJ, Brown TD. Problematic sites of third body embedment in polyethylene for total hip wear acceleration. J. Biomech. 2006;39(7):1208–1216.

Anderson DD, Goldsworthy JK, Shivanna K, Grosland NM, Pedersen DR, Thomas TP, Tochigi Y, Marsh JL, Brown TD. Intra-articular contract stress distributions at the ankle throughout stance phase—Patient specific finite element analysis as a metric of degeneration propensity. Biomech. Model. Mechanobiol. 2006;5(2–3):82–89.

Baer TE, Stolley MP, Thedens DR, Brown TD, Saltzman CL. Development of an MRI and X-ray compatible ankle distraction device. Foot Ankle International. 2006;27(6):472–474.

Kallemeyn NA, Grosland NM, Pedersen DR, Martin JA, Brown TD. Loading and boundary condition influences in a poroelastic finite element model of cartilage stresses in a triaxial compression bioreactor. Iowa Orthop. J. 2006;26:5–16.

Marsh JL, Muehling V, Dirschl D, Hurwitz S, Brown TD, Nepola JV. Tibial plafond fractures treated by articulated external fixation: A randomized trial of postoperative motion versus nonmotion. J. Orthop. Trauma. 2006;20(8):536–541.

Saltzman CL, O’Rourke MR, Zimmerman BM, Buckwalter JA, Brown TD, Johnston RC. Impact of comorbidities on the measurement of health in patients with ankle osteoarthritis. J. Bone Joint Surg. (Am.) 2006 Nov;88(11):2366–72.

McKinley TO, Rudert MJ, Tochigi Y, Pedersen DR, Koos DC, Baer TE, Brown TD. Incongruity-dependent changes of contact stress rates in human cadaveric ankles. J. Orthop. Trauma. 2006 November/December;20(10):732–738.

Brown TD, Johnston RC, Saltzman CL, Marsh JL, Buckwalter JA. Post-traumatic osteoarthritis: A first estimate of incidence, prevalence, and burden of disease. J. Orthop. Trauma. 2006 November/December;20(10):739–744.

Tochigi Y, Rudert MJ, Saltzman CL, Amendola A, Brown TD. The contribution of articular surface geometry to ankle stabilization. J. Bone Joint Surg. (Am.) 2006;88:2704–2713.

Buckwalter JA, Martin JA, Brown TD. Perspectives on chondrocyte mechanobiology and osteoarthritis. Biorheology. 2006;43(3–4):603–9.

Hall RM, Brown TD, Fisher J, Ingham E, Mendoza SA, Meyer HM. Introduction to lumbar total disc replacement: Factors that affect tribologic performance. Proc. Inst. Mech. Eng. [J]: Journal of Engineering Tribology. 2006 Dec;220(8):775–786.

Lundberg HJ, Stewart KJ, Pedersen DR, Callaghan JJ, Brown TD. Non-identical and outlier duty cycles as factors accelerating UHMWPE wear in THA: A finite element exploration. J. Orthop. Res. 2007 Jan;25(1)30–43.

Wall ME, Weinhold PS, Siu T, Brown TD, Banes AJ. Comparison of cellular strain with applied substrate strain in vitro. J. Biomech. 2007;40(1):173–181.

Heiner AD, Callaghan JJ, Brown TD. Stability of fused vs. nonfused THA femoral impaction grafts. J. Orthop. Res. 2007;25(3):351–360.

Anderson DD, Goldsworthy JK, Li W, Rudert MJ, Tochigi Y, Brown TD. Physical validation of a patient-specific contact finite element model of the ankle. 2006 ASB Microstrain Award Paper. J. Biomech. 2007;40(8)1662–1669.

Lundberg HJ, Pedersen DR, Baer TE, Muste MV, Callaghan JJ, Brown TD. Effects of implant design parameters on fluid convection, potentiating 3rd body debris ingress into the bearing surface during THA impingement/subluxation. J. Biomech. 2007;40(8):1676–1685.

Troy (Reed) KL, Lundberg HJ, Conzemius MG, Brown TD. Habitual hip joint activity level of the penned emu (Dromaius Novalehollandie). Iowa Orthop. J. 2007;27:17–23.

Ko C, Brown TD. A fluid-immersed multi-body contact finite element formulation for median nerve stress in the carpal tunnel. Comput. Methods Biomech. Biomed. Engin. 2007 Oct;10(5):343–349.

Goreham-Voss CM, McKinley TO, Brown TD. A finite element exploration of cartilage stress near an articular incongruity during unstable motion. J. Biomech. 2007;50(15):3438–3447.