Thomas D. Brown, PhD

Richard and Janice Johnston Chair of Orthopaedic Biomechanics
Director, Orthopaedic Biomechanics Laboratory

Education

• Case Institute of Technology, Cleveland, OH , Metallurgy
• BS, Mechanical Engineering University of Maryland, College Park, MD, 1972
• MS , Mechanical & BioEngineering, Carnegie-Mellon University, Pittsburgh, PA, 1973
• PhD, Mechanical & BioEngineering, Carnegie-Mellon University, Pittsburgh, PA, 1976

Research and Professional Experience

• 1975-1976 Senior Engineer, Westinghouse Research and Development Center, Churchill, PA
• 1976-1981 Research Assistant Professor of Orthopaedics and Civil Engineering, University of Pittsburgh
• 1981-1983 Research Associate Professor of Orthopaedics and Civil Engineering, University of Pittsburgh
• 1983-1987 Associate Professor of Orthopaedic Surgery and Biomedical Engineering, University of Iowa
• 1987-1997 Professor of Orthopaedic Surgery and Biomedical Engineering, University of Iowa
• 1997-Present Richard and Janice Johnston Chair of Orthopaedic Biomechanics, University of Iowa

Honors and Awards

General Motors Scholar; Elected to Tau Beta Pi, Pi Tau Sigma, and Sigma Xi Honorary Societies; NIH Training Grant Recipient; Giovanni Borelli Award, ASB; Kappa Delta Award, AAOS/ORS; Frank Stinchfield Award (3 times), The Hip Society; Fellow, AIMBE; Clinical Biomechanics Award (2 times), ASB; William Harris Award, ORS; Microstrain Award (2 times), ASB; OREF Clinical Research Award, AAOS; Nicolas Andry Award, ABJS

Organizations

Member of AIMBE; ASME; ASTM (Chairman, F04 Task Group on External Fixation); Society for Biomaterials; ORS [Membership Committee 1984–1988, (Chairman 1986–1987), Board of Directors 1986–1987, 1997–2000, Program Committee 1987–1988, 1991–1992, 1996–1998, (Chairman 1998–1999), President 2001–2002, Chair of the Hip & Knee – Disease Process Topic Committee, 2008-2010]; Society for Experimental Mechanics; American Society of Biomechanics [Program Committee 1985–1988, (Chairman 1987), Executive Committee 1986–1987, 1992–1995, Membership Committee 1988–1992, (Chairman 1991–1992), President 1993–1994]; AAOS (Associate 1986–Present, Committee on Biomedical Engineering 1991–1997, Program Committee 1998–2001; Committee on Research 2002–2006); The Hip Society (Associate 1985–Present, Education Committee 1999–2002); SAS, OARSI; Editorial Consultants Panel, Journal of Biomechanics 1984–Present; Associate Editor, Journal of Orthopaedic Research 1987–1923; Associate Editor, ASME Journal of Biomechanical Engineering 1988–1993; Consulting Editor for Research, Journal of Bone and Joint Surgery 1989–Present; Advisory Panel, International Journal of Orthopaedic Trauma 1995–Present; Editorial Board, Journal of Musculoskeletal Research 1996–present; Editorial Board, Journal of Orthopaedic Trauma, 2005-Present; NIH Orthopaedic and Musculoskeletal Study Section (Regular Member 1989–1993).

Clinical and Research Interests

Orthopaedic Biomechanics
Biomedical Engineering

Recent Publications/Reviews

1. McKinley TO, Rudert MJ, Tochigi Y, Brown TD. Instability-associated changes in contact stress and contact stress rates in human cadaveric ankles. J. Bone Joint Surg. Am. 2008;90(2):375–383. PMC2587164.
2. Goetz JE, Derrick TR, Pedersen DR, Robinson DA, Conzemius MG, Baer TE, Brown TD. Hip joint contact force in the emu (Dromaius novaehollandiae) during normal level walking. J. Biomech. 2008;41(4):770–778. PMC2291359.
3. Thomas TP, Anderson DD, Marsh JL, Brown TD. A method for the estimation of normative bone surface area to aid in objective CT-based fracture severity assessment. Iowa Orthop. J. 2008;28:9–13. PMC2603343.
4. Li W, Anderson DD, Goldsworthy J, Marsh JL, Brown TD. Patient-specific finite element analysis of chronic contact stress exposure after intra-articular fracture of the tibial plafond. J. Orthop. Res. 2008;26(8):1039–1045. PMC2562934.
5. Anderson DD, Mosqueda TV, Thomas TP, Hermanson EL, Brown TD, Marsh JL. Quantifying tibial plafond fracture severity: Absorbed energy and fragment displacement agree with clinical rank ordering. J. Orthop. Res. 2008;26(8):1046–1052. PMC2562904.
6. Heiner AD, Lundberg HJ, Baer TE, Pedersen DR, Callaghan JJ, Brown TD. Effects of episodic subluxation events on third body ingress and embedment in the THA bearing surface. J. Biomech. 2008;41(10):2090–2096. PMC2572990.
7. Heiner AD, Callaghan JJ, Brown TD. Stability differentials for proximal versus distal fusion of THA femoral impaction grafts. J. Arthroplasty. 2008;23(6):921–926. NIHMS68813.
8. Glennon LP, Baer TE, Martin JA, Lack WD, Brown TD. Sliding direction-dependence of polyethylene wear for metal counterface traverse of severe scratches. J. Biomech. Eng. 2008 Oct;130(5): 051006. PMC2593892.
9. Goetz JE, Pedersen DR, Robinson DA, Conzemius MG, Baer TE, Brown TD. The apparent critical isotherm for cryoinsult-induced osteonecrotic lesions in emu femoral heads. J. Biomech. 2008;41(10):2197–2205. PMC2612542.
10. Brown TD, Bartel DL. What design factors influence wear behavior at the bearing surfaces in total joint replacements? Journal of the American Academy of Orthopaedic Surgeons (JAAOS). 2008;16:S101–S106.
11. Paul MC, Glennon LP, Baer TE, Brown TD. Field variable associations with scratch orientation-dependence of UHMWPE wear: A finite element analysis. J. Biomech. Eng. 2008 Dec;130(6):061019. PMC2593842.
12. Tochigi Y, Rudert MJ, McKinley TO, Pedersen DR, Brown TD. Correlation of dynamic cartilage contact stress aberrations with severity of instability in ankle incongruity. J. Orthop. Res. 2008;26(9):1186–1193. PMC Journal – In Process.
13. McKinley TO, Tochigi Y, Rudert MJ, Brown TD. The effect of incongruity and instability on contact stress directional gradients in human cadaveric ankles. Osteoarthritis Cartilage. 2008 Nov;16(11):1363–1369. PMC Journal – In Process.
14. Kang L, Galvin AL, Brown, TD, Jin Z, Fisher J. Wear simulation of UHMWPE hip implants by incorporating the effects of cross-shear and contact pressure. Proc. Inst. Mech. Eng. [H]. 2008;222:1049–1064.
15. Brown TD, Callaghan JJ. Impingement in total hip replacement: Mechanisms and consequences. Curr. Orthop. 2008;22(6): 376–391. PMC Journal – In Process.
16. Moussavi-Harami SF, Pedersen DR, Martin JA, Hillis SL, Brown TD. Automated objective scoring of histologically apparent cartilage degeneration using a custom image analysis program. J. Orthop. Res. 2009;27(4):522–528. PMC Journal – In Process.
17. Segal NA, Anderson DD, Iyer K, Baker J, Torner JC, Brown TD, Lewis CE, Felson DT, Nevitt M. Baseline articular contact stress levels predict incident symptomatic knee osteoarthritis development in the MOST cohort. J. Orthop. Res. 2009 (In press).
18. Rumery MP, Pedersen DR, Mendoza SA, Siepe C, Mayer HM, Brown TD. A pose-based image analysis technique for measuring in vivo wear of total disc replacements. Comput. Methods Biomech. Biomed. Engin. Manuscript ID: GCMB-2007-0059. (Accepted pending minor revision)
19. Anderson DD, Iyer K, Segal NA, Lynch JA, Brown TD. Implementation of discrete element analysis for subject-specific, population-wide investigations of habitual contact stress exposure. J. Appl. Biomech. 2009. (Accepted)
20. Brown TD, Lundberg HJ, Pedersen DR, Callaghan JJ. Clinical biomechanics of third body acceleration of total hip wear. Clin. Orthop. Relat. Res. 2009;467(7):1885–1897. (Accepted for the 2009 Nicolas Andry Award).
21. Altenburg AJ, Callaghan JJ, Yehyawi TM, Pedersen DR, Liu SS, Leinen JA, Dahl KA, Goetz DD, Brown TD, Johnston RC. The effect of cable debris on acetabular construction durability in cemented total hip arthroplasty at 19 to 20 year follow-up. J. Bone Joint Surg. Am. (In press)
22. Hartmann JM, Rudert MJ, Pedersen DR, Baer TE, Goreham-Voss CM, Brown TD. Compliance-dependent load allocation between sensing versus non-sensing portions of a sheet-array contact stress sensor. Iowa Orthop. J. 2009;29:43–47. PMC Journal – In Process.
23. Thomas TP, Anderson DD, Mosqueda TV, Van Hofwegen CJ, Hillis SL, Marsh JL, Brown TD. Objective CT-based metrics of articular fracture severity to assess risk for post-traumatic osteoarthritis. J. Orthop. Trauma. (Accepted pending revision)