Joseph A. Buckwalter, MS, MD

Professor and Head of Orthopaedic Surgery

Medical School

University of Iowa

Residency

University of Iowa

Honors and Awards

• President, Orthopaedic Research Society
• Co-Editor, Journal of Orthopaedic Research
• President, American Board of Orthopaedic Surgery
• President, American Orthopaedic Association
• Founding Fellow of the American Institute of Medical and Biological Engineering
• Fellow Royal College of Surgeons (ed); 2004
• Member Institute of Medicine National Academies of Sciences
• Phi Beta Kappa
• Teacher of the Year, University of Iowa College of Medicine
• Alpha Omega Alpha
• Kappa Delta Award for Outstanding Orthopaedic Research
• Royal College of Surgeons Sir Reginald Watson Jones Lecturer
• Founding Fellow American Institute of Medical and Biological Engineering
• Cabaud Award for Outstanding Research in Sports Medicine
• Bristol-Myers Squibb/Zimmer Award for Distinguished Achievement in Orthopaedic Research

Organizations

• Musculoskeletal Tumor Society
• American Academy of Orthopaedic Surgeons
• Orthopaedic Research Society
• International Skeletal Society
• American Orthopaedic Association
• American Orthopaedic Society for Sports Medicine
• International Society for Limb Salvage
• Girdlestone Orthopaedic Society
• British Orthopaedic Association

Clinical and Research Interests

• Osteoarthritis
• Musculoskeletal Oncology
• Sports Medicine
• Trauma
• Reconstructive Surgery

Recent Publications Selected from over 400

1. Buckwalter JA, Lappin DR: The disproportionate impact of chronic arthralgia and arthritis among women. Clin Orthop Rel Res 372:159-168, 2000.
2. Mehr D, Pardubsky PD, Martin JA, Buckwalter JA: Tenascin-C in tendon regions subjected to compression. J Ortho Res 18:537-545, 2000.
3. Martin JA, Buckwalter JA: The role of chondrocyte-matrix interactions in maintaining and repairing articular cartilage. Biorheology 37:129-140, 2000.
4. Buckwalter JA, Martin JA, Mankin HJ: Synovial joint degeneration and the syndrome of osteoarthritis: Instructional Course Lectures 49:481-489, 2000.
5. Buckwalter JA: Advancing the science and art of orthopaedics- lessons from history. J Bone Joint Surg 82A: 1782-1803, 2000.
6. Martin JA, Buckwalter JA: Telomere erosion and senescence in human articular cartilage chondrocytes. J Gerontology: Biol Sci 56A:B172-B179, 2001.
7. Jones DM, Marsh JL, Nepola JV, Jacobs JJ, Skipor AK, Urban RM, Gilbert JL, Buckwalter JA: Focal osteolysis at the junctions of a modular stainless-steel femoral intramedullary nail. J Bone Joint Surg 83A:537-548, 2001.
8. Buckwalter JA: Articular Cartilage Injuries. Clin Ortho Rel Res 402:21-37, 2002.
9. Martin JA, Buckwalter JA: Aging, articular cartilage chondrocyte senesence and osteoarthritis. Biogerontology 3:257-264, 2002.
10. Martin JA, Mitchell K, Kingelhautz A, Buckwalter JA: Effect of telomerase and proto-oncogene expression on in vitro chondrocyte growth. J Gerontology: Biol Sci 57B: 48-53, 2002.
11. Martin JA, Miller BA, Scherb MB, Lembke LA, Buckwalter JA: Co-localization of insulin-like growth factor binding protein 3 and fibronectin in human articular cartilage. Osteoarthritis Cartilage 10:556-563, 2002.
12. Martin JA, Buckwalter JA: Human chondrocyte senescence and osteoarthritis. Biorheology 39:145-152, 2002.
13. Marsh JL, Buckwalter J, Gelberman R, Dirschl, D, Olson S, Brown, TD, Llinias A: AOA Symposium-Articular Fractures: Does an anatomic reduction really change the result? J Bone Joint Surg 84A:1259-1271, 2002.
14. Martin JA, Forest E, Block JA, Klingelhutz AJ, Whited B, Gitelis S, Wilke A, Buckwalter JA: Malignant transformation in human chondrosarcoma cells is supported by telomerase activation and tumor suppressor inactivation. Cell Growth and Differentiation 13:397-407, 2002.
15. Martin JA, Buckwalter JA: The role of tenascin-C in adaptation of tendons to compressive loading. Biorheology 40:321-329, 2003.
16. Buckwalter JA: Integration of science into orthopaedic practice: implications for solving the problem of articular cartilage repair. J Bone Joint Surg 85A-Supplement 2:1-7, 2003.
17. Martin JA, Buckwalter JA: The Role of Chondrocyte Senescence in the Pathogenesis of Osteoarthritis and in Limiting Cartilage Repair. J Bone Joint Surg 85A-Supplement 2:106-110, 2003.
18. Buckwalter JA, Heckman JD, Petrie DP: Aging of the North American population: new challenges for orthopaedics. J Bone Joint Surg 85A:748-758, 2003.
19. Martin JA, Klingelhutz AJ, Moussavi-Harmi F, Buckwalter JA: Effects of oxidative damage and telmomerase activity on human articular cartilage chondrocyte senscence. J Gerontology: Biol Sciences 59:B324-36, 2004.
20. Buckwalter JA, Brown TD: Joint injury, repair and remodeling: Roles in post-traumatic osteoarthritis. Clin Ortho Rel Res 423:7-16, 2004.
21. Martin JA, Brown T, Heiner A, Buckwalter JA: Post-traumatic Osteoarthritis: The Role of Accelerated Chondrocyte Senescence. Biorheology 41:479-491, 2004.
22. Buckwalter JA, Saltzman C, Brown T: The impact of osteoarthritis: Implications for research. Clin Orthop Rel Res 427S: S6-S15, 2004.
23. Martin JA, Brown TD, Heiner AD, Buckwalter JA: Chondrocyte senescence, joint loading and osteoarthritis. Clin Orthop Rel Res 427S: S96-S103, 2004
24. Martin JA, DeYoung BR, Gitelis S, Weydert JA, Klingelhutz AJ, Kurriger G, Buckwalter JA: Telomerase reverse transcriptase subunit expression is associated with chondrosarcoma malignancy. Clin Orthop Rel Res 426: 117-124, 2004.
25. Buckwalter JA, Mankin HJ, Grodzinsky AJ: Articular cartilage and osteoarthritis. Instructional Course Lectures American Academy of Orthopaedic Surgeons 54: 465-480, 2005.
26. Saltzman CL, Zimmerman MB, O’Rourke M, Brown TD, Buckwalter JA, Johnston R: Impact of comorbidities on the measurement of health in patients with ankle osteoarthritis. J Bone Joint Surg 88A:2366-2372, 2006.
27. Brown TD, Johnston RC, Saltzman CL, Marsh JL, Buckwalter JA: Posttraumatic osteoarthritis: a first estimate of incidence, prevalence and burden of disease. J Orthop Trauma 20:739-744, 2006.
28. Martin JA, Buckwalter JA: Post-traumatic osteoarthritis: The role of stress induced chondrocyte damage. Biorheology 43:517-521, 2006.
29. Buckwalter JA, Martin JA, Brown TD. Perspectives on chondrocyte mechanobiology and osteoarthritis. Biorheology 43(3-4):603-9, 2006.
30. Saltzman CL, Zimmerman MB, O’Rourke M, Brown TD, Buckwalter JA, Johnston R. Impact of comorbidities on the measurement of health in patients with ankle osteoarthritis. J Bone Joint Surg Am 88(11):2366-72, 2006.
31. Zheng H, Martin JA, Duwayri Y, Falcon G, Buckwalter JA. Impact of aging on rat bone marrow-derived stem cell chondrogenesis. J Gerontol A Biol Sci Med Sci. 62(2):136-48, 2007.