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Division of Medical Genetics
Shivanand R. Patil Cytogenetics & Molecular Laboratory
Division of Medical Genetics
Department of Pediatrics
University of Iowa Hospitals and Clinics (UIHC)
W101 GH, 200 Hawkins Dr.
Iowa City, IA 52242
Accreditation/Certification/Proficiency Testing
- Accredited by the College of American Pathologists
(CAP)
- Certified under the Clinical Laboratory Improvements
Amendments of 1988
- Participate in the CAP Cytogenetics Proficiency
Testing (PT) Program
- Director of the laboratory is board certified
in Clinical Pathology and Molecular Genetic Pathology by the American Board of Pathology
Laboratory Director
Benjamin Darbro, MD, PhD, Director
E-mail: benjamin-darbro@uiowa.edu
Laboratory Supervisor/Contact Person
Richard Van Rheeden, BS, MS
Phone: 319-356-3877
richard-vanrheeden@uiowa.edu
Technical Staff Members
- Technologists are well versed in the field of
molecular cytogenetics and experienced in laboratory
methodology; technologists are certified as Clinical Laboratory Specialists in Cytogenetics, CG (ASCP).
- Technologists receive continuing education from attending national and regional meetings, national teleconferences, university seminars, in-house conferences, and participating in laboratory's monthly journal club.
Commitment to providing high quality cytogenetic
services at competitive costs
- Outstanding relationships and interaction with
referring clinicians (obstetricians, neonatologists,
oncologists, pathologists, etc., as well as with other
health care professionals).
- Provides educational and scientific materials to
referring clinicians as needed on unusual cases for the
purpose of aiding counseling and education.
- Participate in Children's Oncology Group (COG) and Cancer of Leukemia Group B (CALGB).
- Certified as reference laboratory by COG and CALGB.
Reporting of Results
- Verbal preliminary results are given in 24-48 hours
based on 10 cells for specimens with hematological
malignancies and newborns suspected of trisomies.
- A written interpretive report of the lab results is available in EPIC for UIHC patients.
- A written report is mailed or faxed to the referring physician at outside hospitals.
- The turnaround times for the final report by specimen
type are shown in the accompanying table.
Confidentiality
- The Cytogenetics and Molecular laboratory is fully committed to
maintaining patient confidentiality.
Consultation
- Consultation is available through our laboratory from
our board certified clinical/molecular/biochemical geneticists and genetic
counselors in the Division of Medical Genetics (phone 319-356-2674).
Requesting Cytogenetic Testing
- A C-12 Cytogenetics Request form (available from our
laboratory) must accompany each specimen sent from outside UIHC.
- All specimens should be sent at room
temperature.Do not freeze or centrifuge.
Billing
- Laboratory fees are submitted to the UIHC Joint Office of Patient Financial Services for processing.
- Complete patient insurance information must accompany
all outside specimens (insurance and authorization forms are attached to the C12 request form).
- If preferred, arrangements can be made to bill
directly to the referring lab or institution.
Research
Hours
- Weekdays:
Monday-Friday
8:00 a.m.-5:00 p.m.
- Weekends/Holidays:
technologists are on week-end call and holiday
Phone and Fax
- (319) 356-3877
- (319) 353-6704 (Fax)
- 1-888-533-0186 (Pager--weekends and holidays
only); press the # sign after you enter your phone number, hang up after the beep
- Weeday after hours in UIHC, page 4291. Outside UIHC, call 319-356-1616 and as the hospital operator to page 4291.
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Test Menu, Specimen Type, and Turnaround Times
| Test and Specimen Type |
Turn Around Times (Days for Final Results) |
| Chromosome Analysis |
| Amniotic Fluid |
10-12 Days |
| Bone
Marrow (for acquired and constitutional abnormalities) |
14 Days |
| Cell Culture (Biochemical and Molecular Studies) |
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| Chorionic Villi |
10-12 Days |
| Fetal Blood (Prenatal Diagnosis) |
7 Days |
| Peripheral Blood (Breakage Studies, Fanconi, AT) |
14-21 Days |
| Peripheral Blood, Cord Blood (Constituional Abnormalities) |
7-14 Days |
| Peripheral Blood for Hematological Disorders |
14 Days |
| Product of Conception (POC) |
21-30 Days |
| Skin, Other Tissue (Constitutional Abnormalities) |
21-30 Days |
| Skin or Internal Tissue or Blood from Autopsy (Constitutional Abnormalities) |
21-30 Days (tissues) 14-21 Days (blood) |
| FISH (Fluorescence In-Situ Hybridization) |
| Amniocytes, Chorionic Villi (Prenatal-Aneuploidy/Microdeletion) |
2-10 Days |
| Bone Marrow |
3-5 Days |
| Peripheral Blood (Hematological) |
3-5 Days |
| Peripheral Blood (Newborn or Cord, and Others) (Aneuploidy Screening) |
2-5 Days |
| Peripheral Blood, Bone Marrow, Fibroblasts, Other Tissue (Microdeletion and subtelomeric constitutional studies) |
5-7 Days |
| Tumor Tissue (Fresh Tissue) |
7-14 Days |
| Tumor Tissue (Paraffin Embedded Tissue Slides) |
3-10 Days |
| Voided Urine, Bladder Wash (Bladder Carcinoma) |
4-8 Days |
Chromosome Micro Array (CMA) |
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| Peripheral Blood (Purple Top)-for Constitutional Abnormalities |
4 weeks |
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Shipping
- Specimens should be sent by overnight courier. If
arrival will occur on the weekend, specimens should be
delivered to Specimen Control, UIHC, 6240 RCP, ATTN: Cytogenetics and Molecular Lab.
Please call the Cytogenetics Laboratory and leave patient
name, specimen type, referring physician's name and phone
number, and tracking number of courier recorded on our
voice mail.
- We can provide a Fed Ex account number for shipping
charges on a case by case basis.
Supplies
- Styrofoam mailers are available from our laboratory for out-of-hospital clients (contact the laboratory for specific details).
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