Titles
Director, Pediatric Cardiology Fellowship Program
Assistant Professor of Pediatrics
Education
BS – University of Arizona; 1991
MD – University of Arizona; 1995
Postgraduate Training
Residency – University of Arizona
Pediatric Cardiology Fellowship – University of Iowa
Clinical Interests
Congenital and acquired heart disease in children; adults with congenital heart disease; connective tissue disorders, cardiomyopathy, and heart transplantation.
Research Interests
Research in our laboratory centers on cardiac development and the origins of congenital heart disease. Areas of focus include identification and characterization of genes critical to development and physiology of the embryonic conduction system.
Current studies concentrate on the role of the transcription factor, Nkx 2.5, on development of the embryonic cardiac conduction system. We utilize an array of techniques to modulate gene expression and monitor cardiac development through embryogenesis to adulthood.
Confocal micrograph of a stage 46 Xenopus heart. Staining for actin (blue) and acetylated tubulin (green) allows imaging of the heart and conduction system, that starts high in the right atrium, bridges the atrioventricular junction and bifurcates into two branches in the ventricle (arrows).
Lab Members
Elesa Wedemeyer
Collaboration with the laboratory of Dan Weeks, Ph.D.
Model System
Xenopus laevis and Xenopus tropicalis
Recent Publications
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