Titles
Director, Pediatric Cardiology Fellowship Program
Director, Adolescent and Adult Congential Heart Disease Program
Assistant Professor of Pediatrics and Biochemistry
Education
BS – University of Arizona; 1991
MD – University of Arizona; 1995
Postgraduate Training
Residency – University of Arizona
Pediatric Cardiology Fellowship – University of Iowa
Clinical Interests
Congenital and acquired heart disease in children; adults with congenital heart disease; connective tissue disorders, cardiomyopathy, and heart transplantation.
Research Interests
Research in our laboratory centers on the molecular origins of cardiovascular disease. Current studies concentrate on mutations in alpha-smooth muscle actin that cause a range of cardiovascular diseases in children and adults, including Familial Thoracic Aortic Aneurysm and Dissection. We are working to determine the components of actin function and regulation that are perturbed in vascular disease. We use the yeast expression system for detailed studies on the effects of the mutations in vivo and in vitro.
Lab Members
Elesa Wedemeyer
Alyson Pierick
Nicki Vanderpool
Sarah Bergeron
in collaboration with the laboratories of Peter Rubenstein, Ph.D. and Dan Weeks, Ph.D. in the Department of Biochemistry.
Recent Publications
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