Edward F. Bell, MD
Research Profile

• Thermal physiology of the newborn infant
• Water and electrolyte homeostasis
• Energy and substrate utilization
• Anemia and transfusion of the preterm infant
• Clinical trials relating management to outcome in NICU patients

Affiliations:

• Department of Pediatrics
• Division of Neonatology
• NICHD Neonatal Research Network, principal investigator for University of Iowa site

Lab Members:

• Karen Johnson, R.N., Coordinator, NICHD Neonatal Research Network

Recent Publications:

1. Bell EF, Strauss RG, Widness JA, Mahoney LT, Mock DM, Seward VJ, Cress GA, Johnson KJ, Kromer IJ, Zimmerman MB.  Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants.  Pediatrics.  2005; 115:1685-91.
2. Strauss RG, Mock DM, Johnson KJ, Cress GA, Burmeister LF, Zimmerman MB, Bell EF, Rijhsinghani A.  A randomized clinical trial comparing immediate versus delayed clamping of the umbilical cord in preterm infants: short-term clinical and laboratory endpoints.  Transfusion.  2008; 48:658-65.  Epub 2008 Jan 10.
3. Bell EF, Acarregui MJ.  Restricted versus liberal water intake for preventing morbidity and mortality in preterm infants.  Cochrane Database Syst Rev. 2008; (1):CD000503.
4. Colaizy TT, Younis UMM, Bell EF, Klein JM.  Nasal high-frequency ventilation for premature infants.  Acta Paediatr.  2008; 97:1518-22.  Epub 2008 Jun 9.
5. Bell EF.  When to transfuse preterm babies.  Arch Dis Child Fetal Neonatal Ed.  2008; 93:F469-73.  Epub 2008 Jul 24.
6. Spanos WC, Brookes JT, Smith MC, Burkhart HM, Bell EF, Smith RJH.  Unilateral vocal fold paralysis in premature infants after ligation of patent ductus arteriosus: vascular clip versus suture ligature.  Ann Otol Rhinol Laryngol.  2009; 118:750-3.
7. Zeitoun AA, Gad SS, Attia FM, Abu Maziad AS, Bell EF.  Evaluation of neutrophilic CD64, interleukin 10 and procalcitonin as diagnostic markers of early- and late-onset neonatal sepsis.  Scand J Infect Dis.  2010; 42:299-305.  Epub 2010 Jan 19.
8. Abu-Maziad AS, Schaa KL, Bell EF, Dagle JM, Cooper M, Marazita ML, Murray JC.  Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.  Pediatr Res.  2010; 68:323-9.  Epub 2010 May 11.
9. Carlo WA, Finer NN, Walsh MC, Rich W, Gantz M, Laptook AR, Yoder BA, Faix RG, Das A, Poole WK, Schibler K, Newman N, Frantz ID III, Sanchez PJ, Buchter S, Morris BH, Laroia N, Poindexter BB, Cotten CM, Van Meurs KP, Sood B, Duara S, O’Shea TM, Bell EF, Ehrenkranz RA, Watterberg KL, Higgins RD, for the NICHD Neonatal Research Network.  Target ranges of oxygen saturation in extremely preterm infants  N Engl J Med.  2010; 362:1959-69.  Epub 2010 May 16.
10. Finer NN, Carlo WA, Walsh MC, Rich W, Gantz M, Laptook AR, Yoder BA, Faix RG, Das A, Poole WK, Schibler K, Donovan E, Narendran V, Newman N, Frantz ID III, Sanchez PJ, Buchter S, Morris BH, Laroia N, Poindexter BB, Cotten CM, Van Meurs KP, Sood B, Duara S, O’Shea TM, Bell EF, Bhandari V, Watterberg KL, Higgins RD, for the NICHD Neonatal Research Network.  Early CPAP versus surfactant in extremely preterm infants.  N Engl J Med.  2010; 362:1970-9.  Epub 2010 May 16.
11. Davis AS, Hintz SR, Van Meurs KP, Li L, Das A, Stoll BJ, Walsh MC, Pappas A, Bell EF, Laptook AR, Higgins RD, for the NICHD Neonatal Research Network.  Seizures in extremely low birth weight infants are associated with adverse outcomes.  J Pediatr.  2010; 157:720-5.e1-2.  Epub 2010 Jun 14.
12. Bell EF, Hansen NI, Morriss FH Jr, Stoll BJ, Ambalavanan N, Gould JB, Laptook AR, Walsh MC, Carlo WA, Shankaran S, Das A, Higgins RD, for the NICHD Neonatal Research Network.  Impact of timing of birth and resident duty-hour restrictions on outcome of small preterm infants.  Pediatrics.  2010; 126:222-31.  Epub 2010 Jul 19.
13. Stoll BJ, Hansen NI, Bell EF, Shankaran S, Laptook AR, Walsh MC, Hale EC, Newman NS, Schibler K, Carlo WA, Kennedy K, Poindexter BB, Finer NN, Ehrenkranz RA, Duara S, Sanchez PJ, O’Shea TM, Goldberg RN, Van Meurs KP, Faix RG, Phelps DL, Frantz ID III, Watterberg KL, Saha S, Das A, Higgins RD, for the NICHD Neonatal Research Network.  Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network.  Pediatrics.  2010; 126:443-56.  Epub 2010 Aug 23.
14. Benjamin DK Jr, Stoll BJ, Gantz MG, Walsh MC, Sanchez PJ, Das A, Shankaran S, Higgins RD, Auten KJ, Miller NA, Walsh TJ, Laptook AR, Carlo WA, Kennedy KA, Finer NN, Duara S, Schibler K, Chapman RL, Van Meurs KP, Frantz ID III, Phelps DL, Poindexter BB, Bell EF, O’Shea TM, Watterberg KL, Goldberg RN, for the NICHD Neonatal Research Network.  Neonatal candidiasis: epidemiology, risk factors, and clinical judgment.  Pediatrics.  2010; 126:e865-73.  Epub 2010 Sep 27.
15. Kao JS, Dawson JD, Murray JC, Dagle JM, Berends SK, Gillen SB, Bell EF.  Possible roles of bilirubin and breast milk in protection against retinopathy of prematurity.  Acta Paediatr.  Epub 2010 Oct 22.
16. Fredrickson LK, Bell EF, Cress GA, Johnson KJ, Zimmerman MB, Mahoney LT, Widness JA, Strauss RG.  Acute physiological effects of packed RBC transfusion in preterm infants with different degrees of anaemia.  Arch Dis Child Fetal Neonatal Ed.  Epub 2010 Nov 20.
17. Boghossian NS, Hansen NI, Bell EF, Stoll BJ, Murray JC, Laptook AR, Shankaran S, Walsh MC, Das A, Higgins RD, for the NICHD Neonatal Research Network.  Survival and morbidity outcomes of very low birth weight infants with Down syndrome.  Pediatrics.  2010; 126:1132-40.  Epub 2010 Nov 22.
18. Hintz SR, Kendrick DE, Wilson-Costello D, Das A, Bell EF, Vohr BR, Higgins RD, for the NICHD Neonatal Research Network.  Neurodevelopmental outcomes in early childhood are not improving for extremely preterm infants born at less than 25 weeks gestational age.  Pediatrics.  2011; 127:62-70.  Epub 2010 Dec 27.
19. Bell EF, Zumbach DK.  The tiniest babies: a registry of survivors with birth weight below 400 grams.  Pediatrics.  2011; 127:58-61.  Epub 2010 Dec 27.
20. Nopoulos PC, Conrad AL, Bell EF, Strauss RG, Widness JA, Magnotta VA, Zimmerman MB, Georgieff MK, Lindgren SD, Richman LC.  Long-term outcome of brain structure in premature infants: effects of liberal versus restricted red blood cell transfusions.  Arch Pediatr Adolesc Med.  Epub 2011 Jan 3.