Titles
Director, Division of Pediatric Nephrology, Dialysis & Transplantation
Director, Pediatric Dialysis Services
Director, Pediatric Renal Transplantation
Director, Pediatric Nephrology Fellowship Program
Co-Director, University of Iowa ECMO program
Associate Professor of Pediatrics

Education
BSc (biochemistry)– University of Regina; 1988
BA-(Hons- Physiologic Pyschology) University of Saskatchewan; 1992
MD – University of Saskatchewan College of Medicine; 1994

Postgraduate Education
Residency – University of Manitoba
Fellowship – University of Michigan

Clinical Interests

• Antenatal renal abnormalities and Polycystic Kidney Disease
• Acute Kidney Injury and Critical Care Nephrology
• Extracorporeal therapies including; Continuous Renal Replacement Therapy, hepatic support, therapeutic plasma exchange ECMO, Dialysis (Acute and Chronic)
• Rare renal diseases such as Membranoproliferative Glomerulonephritis (MPGN) and atypical Hemolytic Uremic Syndrome
• Transplantation
  

Research Interests

1. Basic Science interests: 1) The genetic and developmental biology aspects underlying kidney formation, 2) Congenital and Genetic urogenital abnormalities – more specifically Bilateral/Unilateral renal agenesis (Potter’s Syndrome) and congenital progressive hydronephrosis.
2. Translational/Collaborative Interests: Transplantation and Renal biobanks, Membranoproliferative Glomerulonephritis (MPGN) and atypical Hemolytic Uremic Syndrome
3. Clinical Interests: member of the Prospective Pediatric Continuous Renal Replacement Therapy Registry, NAPRTCS, Chronic Kidney Disease, Acute Dialysis Quality Initiative (ADQI) and Acute Kidney Injury Network (AKIN).

Potter’s Syndrome Genetics study

Congenital progressive hydronephrosis

Research Team /Lab Members

• Jason Clarke Research Assistant III- Lab Manager
• Erik Bunchman BSc Research Assistant I
• Courtney Harkness Translational Research Assistant II

Research Affiliations

• Division of Nephrology Genetics (in process)
• Molecular & Cell biology (in process)
• Midwest Pediatric Nephrology Consortium
• NAPRTCS

Model System

Animal models: predominantly mice, in vitro cell culture model systems, translational research-Human genetic biobanks and databases.

Human clinical and outcomes trials (main focus Critical care based nephrology: Renal Supportive Therapies, Plasma exchange, hepatic dialysis and Extra-corporeal membranous oxygenation).

Recent Publications

Back to the Department of Pediatrics

Division of Pediatric Nephrology, Dialysis & Transplantation

Recent Publications

Contact Information:
Office: 319-384-3090
E-mail: patrick-brophy@uiowa.edu