Title
Professor, Infectious Diseases
Education
BA – Beloit College; 1963
MD – University of Chicago School of Medicine; 1967
Postgraduate Training
Residency – Albert Einstein College of Medicine
Pediatric Infectious Diseases Fellowship – Albert Einstein College of Medicine
Immunology Postdoc Fellowship – University of California
Research Interests
Varicella-zoster virus. VZV is the virus that causes chickenpox in children and shingles in the elderly. We study the components of the virus. We use a variety of molecular biology techniques. We also use the newest imaging techniques, to determine the sites on the virus that interact with the cell. Of recent interest, we have discovered the first mutant strain of varicella-zoster ever found anywhere in the world.
Human herpes virus type 8. HHV-8 causes Kaposi sarcoma in AIDS patients. However, 3 to 5% of otherwise healthy people in the United States are infected with this virus. It is not known how this virus is transmitted from person to person. We are currently studying neonates in Iowa to determine if the virus is transmitted at time of delivery or shortly thereafter.
Lab Members
- Lucie Maresova, PhD
- Minako Oda, PhD
- John Storlie, BS
- Wallen Jackson, BS
- Victor Estrada
Grose Lab Website
Affiliations
- Department of Pediatrics
- Center for Emerging Infectious Diseases
- Iowa Biosciences Advantage program for minority students.
Our research is carried out in collaboration with groups at the National Microbiology Laboratory in Winnipeg, MB, Canada; Stanford University, California, and University of Buffalo, New York.
Model System
Cell culture models of virus infection and virus transfection with individual genes.. Studies on human volunteers, including newborns.
Recent Publications
Back to Department of Pediatrics
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Division of Infectious Diseases
Recent Publications
Contact Information:
E-Mail: charles-grose@uiowa.edu |
