Title
Assistant Professor, Hematology/Oncology
Education
BS – University of Minnesota; 1984
PhD – University of Minnesota; 1995
Postgraduate Training
Postdoctoral Fellowship – University of Iowa
Microbiology Fellowship – University of Iowa
Research Interests
The major aim of my research is to characterize the mechanisms by which members of the TNF receptor family deliver signals to cells of the immune system. Members of this interesting and growing family of receptors regulate cellular activation, differentiation, and programmed cell death in a wide variety of cell types. While these proteins appear to share many intracellular signaling molecules, each receptor delivers its own unique signals. Characterizing the signaling pathways involved will potentially lead to novel ways of modulating immune activation in infection, cancer, graft rejection, and autoimmunity.
Lab Members
Mikaela Grove, RA1
Affiliations:
Model System
We primarily utilize cell lines in vitro in characterizing the signaling mechanisms used by the by the TNFR family. Our work involves immunology, cell biology, molecular biology, and biochemistry.
Recent Publications
Back to Department of Pediatrics
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Division of Hematology Oncology
Recent Publications
Contact Information:
E-mail: bruce-hostager@uiowa.edu
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