University of Iowa Hospitals and Clinics
Professor
Department of Pediatrics

Medical/Graduate School
Karnataka University
Colorado University

Fellowship
University of Colorado Medical Center, Medical Cytogenetics

Research Interests
Interested in the association of genetic defects with chromosome abnormalities. Cytogenetic studies are utilized to detect chromosomal rearrangements in individuals with congenital malformations and/or mental retardation, malignancies and other genetic disorders.

Recent Publications

1. Wassink, T., Losh, M., Piven, J., Sheffield, V.C., Ashley, E., Westin, E. and Patil, S.R.:   Systematic screening for subtelomeric anomalies in a clinical sample of sutoism.   J. Autism & Develop. Disorders (in press).
2. Heerema, N.A., Shuster, J., Biegel, J., Camitta, B., Cooley, L.D., Gaynon, P.S., Hirsch, B., Magenis, E. H., McGavran, L., Patil, S., Pettinati, M.J., Pullen, J., Raimondi, S.C., Rao, K., Schneider, N.R., Roulston, D., Sanger, W., Sather, H.N., Sutcliff, M.J., van Tuinen, P., Watson, M.S., Carroll, A.J.: Extra copy numbers of specific chromosomes occur in an identifiable pattern at each modal number and are cumulative in pediatric acute lymphoblastic leukemia. Genes, Chromosomes & Cancer, 46:684-693, 2007.
3. Felix, T.M.,Tansey, M.J.,Patil, S.R., Murray, J.C.,Dagle, J.M.: Double paternal nondisjunction in an infant with transient neonatal diabetes mellitus and Klinefelter syndrome. Amer. J. Med. Genet.   143A:895-898, 2007.
4. Klingelhutz, A.J., Qian, Q, Phillips, S, Gourtrone, F.A., Darbro, B.W. and Patil, S.R..: Amplification of chromosome 20q region is associated with expression of HPV-16 E7 in human airway and anogenital epithelial cells. Virology 340:237-244, 2005.
5. Di Paola, J, Goldman, T, Qian, Q. Patil, S.R. and Schute, B.: Breakpoint of a balanced translocation (X;14)(q27.1;q32.33) in a girl with severe hemophilia B maps proximal to the factor   IX gene. J.Thromb. Haemost. 2: 437-440, 2004.

E-mail: shivanand-patil@uiowa.edu