Jeffrey L. Segar, MD


Titles
Director, Division of Neonatology
Professor of Pediatrics

Education
BS – University of Wisconsin; 1982
MD – University of Wisconsin; 1986

Postgraduate Training
Residency – University of Iowa
Neonatology Fellowship – University of Iowa

Clinical Interests
Optimization of pharmacologic closure of patent ductus arteriosus

Research Interests
Developmental cardiovascular biology; Integrative neural regulation of cardiovascular function; developmental programming of adult cardiovascular disease.

Our research focuses on developmental cardiovascular biology. We are presently investigating cellular and molecular adaptations of the fetal heart to increased work load. This work is performed primarily in the fetal sheep and involves a number of surgical and benchtop investigations.

We are also very interested in the field of "fetal programming", the concept that the intrauterine environment plays a powerful role in determining risks for adult onset diseases, such as hypertension, coronary artery disease and diabetes. We are taking a multidisciplinary approach to investigate mechanisms of hypertension and coronary artery dysfunction.

Research Team/Lab Members
Thomas D. Scholz, MD
Fred Lamb, MD, PhD
Robert D. Roghair, MD
Ben Reinking, MD
Kurt Bedell

Research Affiliations
Department of Pediatrics, Division of Neonatology
Department of Pediatrics, Division of Pediatric Cardiology
Department of Pediatrics, Division of Critical Care
Department of Internal Medicine, Division of Cardiology
Department of Anatomy & Cell Biology

Model System
Fetal and newborn sheep
Molecular and cell biology
Myocyte culture

Recent Publications

Back to Department of Pediatrics

Jeffrey L. Segar, MD

Division of Neonatology

Recent Publications

Contact Information:
Office: 319-356-7244
Fax: 319-356-4685
Lab: 319-335-6997
E-mail: jeffrey-segar@uiowa.edu


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Last modification date: Wed Mar 18 15:26:11 2009
URL: http://www.uihealthcare.com /depts/med/pediatrics/pedsmds/segar.html