Tests the use of the medication risperidone for behavior problems that may occur in persons with memory problems

These may include distressing behaviors, unusual perceptions, and/or emotions in persons with memory disorders (dementia)

This study seeks to treat behavior, not the memory problem.

Who May Participate?
People diagnosed with Alzheimer’s disease, who are having difficulties with:

• Seeing or hearing things that no one else can see or hear
• Having ideas or worries that are unfounded
• Having problems involving being angry, restless, nervous, or irritable for no apparent reason

What is Involved?

• The study will last for a maximum of nine months
• The study involves research medication (FDA-approved) and/or placebo (sugar pill) provided at no cost
• It involves meeting with the study team regularly to assess specific problem
• The visits would occur on several occasions during the study to evaluate any changes in symptoms, caregiver burden, and your overall health

Symptoms of Alzheimer’s

• Misplacing/losing things
• Accusing others of taking or misplacing items that are missing
• Forgetting words and phrases in conversation
• Misremembering past events
• Confusion over date and time
• Repetitive questioning
• Wandering
• Increased disorientation
• Agitation
• Abrupt changes in mood

For more information on this study, please contact:

Karen Smith, RN
Research Assistant
2-213 MEB
Iowa City, IA 52242
Phone: 319-353-5158