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Treatment Options

Autism Spectrum and Developmental Disorders Clinic

Medical Treatments
Currently there is no cure available for Autism, however, medical treatments are available to alleviate symptoms, including attention-related problems, obsessiveness (behavioral rigidity) and aggressiveness.

An evaluation should determine the symptoms that might be amenable to medical treatment. Any concurrent symptoms should be considered. Lastly, side effects should be explained.

Attention deficit

  • Analeptics: Ritalin (methylphenidate), Dexedrine (dextroamphetamine)—These medications can improve attention and reduce impulsivity. However their powerful effects must be monitored for side effects including anorexia and insomnia.
  • Clonidine and Tenex (guanfacine)—Both are alpha-adrenergic presynaptic agonists. They can benefit attention and other symptoms
  • Tricyclics—Tricyclics like imipramine or nortriptyline can benefit ADHD symptoms. Use of these medications should be monitored carefully for possible side effects, including cardiac related problems.

Compulsive behaviors, rituals, and behavioral rigidity

  • SSRIs: Prozac, Luvox, Zoloft, Paxil, Celexa (fluoxetine, fluvoxamine, sertraline, citalopram, paroxetine)—In conservative doses these medications can reduce compulsive symptoms safely.
  • Anafranil (clomipramine)—This is a tricyclic medicine with serotonin actions.
  • Neuroleptics: Risperidone , olanzapine, and the more traditional: Haldol, etc.—Especially the 'atypical' newer medications (even though there may not be differences in response). These are powerful medications, which can produce good results with careful monitoring.

Agitation and aggression
The treatment of aggressive behaviors can be complicated. The clinician should try to determine when, where, and why aggression is occurring. The following medications might be useful in reducing aggressive behaviors.

  • SSRIs (Prozac, etc.)
  • Mood stabilizers
    • Tegretol and Depakote
  • Neuroleptics, including risperidone
  • Tricyclics
  • Tenex and clonidine
  • Naltrexone

 

Last modification date: Fri Aug 15 13:12:41 2008
URL: http://www.uihealthcare.com /depts/uibehavioralhealth/patients/autismspectrum/treatment.html