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    University of Iowa Health Care Today June 2007

IntraLase®-Enabled Keratoplasty


Earlier this spring, University of Iowa Hospitals and Clinics Department of Ophthalmology and Visual Sciences became the first to provide a new laser-based cornea transplant procedure. Kenneth Goins, MD, ophthalmologist in the cornea and external disease/refractive laser surgery clinic at UI Hospitals and Clinics and the surgeon to perform the first IEK procedure, talks more about the IntraLase ® -Enabled Keratoplasty or IEK procedure.

What happens to an eye to require a cornea transplant?

The most common cause for corneal transplantation in the United States is an acquired or inherited dysfunction of the corneal endothelium, which is a layer of tissue responsible for maintaining corneal clarity. Then, inherited disorders, such as keratoconus and acquired non-traumatic ailments such as herpes simplex infection, are the next most common reasons for corneal transplantation.

Who qualifies for a cornea transplant?

Because the cornea does not have a blood supply and receives it nutrients from the tear film and aqueous in the eye, the risk of rejection is much less compared to other types of organ transplantation. Therefore, it is rare for a patient in need not to qualify for a corneal transplant.

What does the conventional procedure for a cornea transplant include?

Standard corneal transplantation uses manual trephine blades to create vertical edge corneal wounds in both the donor and recipient. The transplant is then secured into position with 16 to 24 nylon sutures, or stitches. Visual rehabilitation may take up to one year as these sutures are removed. In layman's terms, basically we're cutting the eye and sewing a new piece back on.

How does the IEK procedure differ from the conventional surgery?

With IEK, a surgeon can create customized incisions that provide greater surface area, a smoother corneal contour, and greater wound strength. These are benefits that have not been possible with standard corneal transplantation.

What are the clinical benefits of an IEK procedure?

IEK may lead to a reduced number of corneal sutures and secondary astigmatism, a decreased risk for wound dehiscence and infection after surgery, and faster visual recovery for the patient.

Will the IEK procedure make it possible for people who may not have previously qualified for a cornea transplant to qualify now?

No, IEK is not expected to increase the number of patients who are candidates for corneal transplantation, although more research is needed to confirm this observation.

If someone wanted to learn more about the IEK procedure whom would they contact ?

They should contact the Division of Refractive Surgery at the University of Iowa either by e-mail using l asik@uiowa.edu or by phone, 319-353-7625.

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Last modification date: Fri Dec 21 10:56:32 2007
URL: http://www.uihealthcare.com /kxic/2007/june/corneaTransplant.html